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Literature-based
followup recommendations
Part 4: Myelodysplastic and myeloproliferative
syndromes and management of iron overload in multiply-transfused
oncology patients
Malcolm Brigden, MD, FRCPC, FACP;
Shahid Ahmed, MD, FRCPC; Richard Wells, MD, PhD, FRCPC
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here (pdf format)
Abstract
Many smaller Canadian cancer centres or those employing hematologists
to manage malignant hematology as a community service often follow
patients with myelodysplastic or myeloproliferative syndromes. Similarly,
most cancer programs will have a number of patients dependent on
regular transfusion support who also require management for potential
iron overload. There are few randomized studies in these conditions
and best practice is, by necessity, literature-based. This article
reviews practical aspects of followup of these syndromes, as well
as management of iron overload in the multiply-transfused oncology
patient.
Key words: myelodysplastic disorders, myeloproliferative
syndromes, hematology, transfusion, myelofibrosis, thrombocythemia,
polycythemia, iron chelation, iron overload.
To view the complete article click
here (pdf format)
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